How Long Do the Effects of CBD Last?

Whether you’ve taken CBD for the first time or you’ve been loving the results and have been dutifully building up the levels of CBD in your system—you might have wondered how long the effects will last. As with dosage and timing, while there is no ‘one-size-fits-all” approach, there are factors that influence how long you’ll experience the effects of this balance-restoring compound. 

How does CBD work in the body?

CBD works by activating receptors and neurotransmitters through a network of cannabinoids called the endocannabinoid system (ECS).

Unlike THC, which binds directly to CB-1 receptors located in the brain, CBD works in the body by manipulating receptors throughout organ tissues, the immune system, the pain response system, the hormonal system, and other whole-body regulatory systems. CBD receptors have been found in virtually every cell and tissue type in the body. For this reason, CBD is believed to work on many aspects of human health and behavior – from the subcellular level to the whole-body level and beyond.

CBD is therapeutic in that it manipulates body systems at the cellular level and returns afflicted organ systems, tissue systems, and even chemical systems in the central nervous system back to a state of health and homeostasis. This is why it has been capable of treating conditions such as depression and anxiety, as well as chronic physical ailments such as pain, inflammation, arthritis, and more.

What does CBD help with?

Aside from two rare forms of epilepsy, the FDA does not recognize the medical use of CBD for any medical condition. That said, numerous reports have shown that the compound may have beneficial effects on a variety of conditions and ailments. Many have claimed that CBD oil helps them with the challenges of:

Alzheimer’s disease





Chronic pain


Epilepsy (seizures)

Inflammation from various conditions


Multiple Sclerosis

Nausea (emesis)


Post-Traumatic Stress Disorder (PTSD)